One of my advice to designer who ask me about XR application design is that to stop thinking in 2D.
I learned that from reading the works of Rowena Reed Kostellow, the pioneer American industrial design professor.
Rowena was adamant that the only way to create 3 dimensional forms was to work 3 dimensionally. It was her mantra “all 3 dimensional projects should be designed 3 dimensionally. You can’t develop a good 3-D design on paper. That’s like drawing a piece of sculpture. You have to deal with negative space , & you can’t do that in 2 dimensions.
Elements of Design